Claire was a PhD student in the group from 2007-2010. Her project centred on the HCV receptor tetraspanin CD81. Tetraspanins are cell membrane proteins; their functions are cell type and tetraspanin dependent and include proliferation, adhesion and motility. She investigated the function of CD81 in hepatoma biology and the effect of HCV infection on these processes.
Alongside this she also investigating receptor dependency of cell-cell and cell free routes of HCV transmission using an in vitro co-culture transmission assay. Claire is now a Post Doc in Cancer Sciences here in Birmingham
School of Cancer Sciences,
College of Medical and Dental Sciences,
University of Birmingham, Birmingham B15 2TT UK
Tel: 0121 414 8173
E-mail: Claire Brimacombe